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Tier 1 brief - Format preview
What a Tier 1 brief looks like
One commissioned question. Audit-grade synthesis. 10-15 page PDF dossier plus a slide-deck extract you can drop into internal presentations. Five business days from signed intake.
Preview only. The slide mockups below show structure and provenance discipline, not full content. Real Tier 1 briefs are commissioned to one client question - not published publicly. To see a longer deliverable (T2 dossier), open the
ITP T-PO RA vs FcRn excerpt.
Specs
Turnaround
5 business days
Deliverables
What you get
- PDF dossier (10-15 pages, per-claim tier-classified)
- Slide-deck extract (key findings, internal-presentation-ready)
- Locked anchor source set (EMA, FDA, CT.gov, EHA, ASH, EULAR, AACR, ASCO, ESMO, PubMed)
- One peer reviewer pass
- One revision round
- Confidential footer + audit trail
What you do not get
- KOL primary research interviews
- Quarterly forecasting
- Investment recommendations
- Single-asset hit pieces
- Recycled syndicated content
Slide-deck extract structure
Four representative slides from a Tier 1 deck. Real decks are scoped to your question. Provenance tags carry from PDF to deck so every chart, number, and claim survives downstream forwarding. A full 6-slide example, filled with public ITP modality content, is available below.
Download example deck (PDF, 6 slides, 48 KB)
Slide 01
Cover · scope
[Client question, restated verbatim from intake]
Indication · modality class · time horizon · stakeholder lens. Snapshot date locked. Anchor sources declared upfront.
EMA
FDA
ClinicalTrials.gov
PubMed
EHA / ASH / ASCO
Slide 02
Finding 01 · headline
One-sentence finding the reader needs to remember
Supporting evidence below. Every line carries a tier label.
| Claim | Tier | Source |
|---|
| [Numerical anchor from RCT] | Sourced | Trial NCT###### / EMA label |
| [Cross-trial comparison] | Inferred | Indirect, no head-to-head |
| [Forward-looking signal] | Hedged | Editorial interpretation |
Slide 03
Finding 02 · competitive sequencing
How this slots into the live competitive set
Full class context. No single-asset hit piece. Reader sees the asset framed against direct peers + adjacent modalities.
- [Modality A] - [mechanism position, evidence-tier-labeled]
- [Modality B] - [mechanism position, evidence-tier-labeled]
- [Modality C] - [mechanism position, evidence-tier-labeled]
- Whitespace gap: [specific unanswered question that survives this analysis]
Slide 04
Methodology · audit
Methodology, sources, what was checked, what was excluded
Gate A: deep-research verification pass. Gate B: LLM-council adversarial review. One peer reviewer pass. Every claim audit-traceable.
- Anchor sources consulted (full list)
- Snapshot date + staleness rule (>90d triggers banner)
- Exclusions: what was looked at and not used, with reason
- Reviewer + revision history